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Vein Care 30 Caps  

Vein Care 30 Capsules NEW

Vein support formula With horse chestnut, rutin & proanthocyanidins

Only NZ$31.95

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Products Information

Vein-care is a special formulation containing potent herbs, rutin and proanthocyanidins. These nutrients help to protect the integrity of veins and capillaries, as well as tone and strengthen vein walls. The ingredients in Vein-care support healthy vein and capillary function, and aid the blood circulation in the lower extremities.


Adults – Take 1 capsule 2-3 times daily with food, or as professionally recommended.


Grape seed      5260mg (Providing Proanthocyanidins 50mg)
Horse chestnut 3750mg
Ginkgo biloba   1000mg
Rutin                200mg
Gotu kola          150mg
This product contains encapsulating aids. Some herbal extract used.

Seek professional health advice if pregnant, lactating, suffering from a medical condition or taking medication before supplementing. In rare cases, this product may cause an allergic reaction and gastrointestinal discomfort.


Vein support formula vein-care With horse chestnut, rutin & proanthocyanidins

Chronic venous insufficiency (CVI) is a medical condition where the veins cannot pump enough oxygen-poor blood from feet and legs back to the heart. This is due to damaged or "incompetent" valves in leg veins to hold blood against gravity, leading to sluggish movement of blood out of the veins, resulting in swollen legs, often accompanied by a dull ache made worse with prolonged standing. It may occur following excessive clotting and inflammation of the leg veins, a disease known as deep vein thrombosis. If CVI is allowed to progress, the skin tends to darken and ulcers may occur.  

 CVI often causes varicose veins, which are twisted, enlarged veins close to the surface. They can occur almost anywhere but most commonly occur in the esophagus and the legs. Veins, which return blood to the heart, contain valves that keep blood from flowing backward as a result of gravity. When these valves become weak, blood pools in the veins of the legs and causes them to bulge. These enlarged vessels are called varicose veins.

Standing and sitting for long periods of time, lack of exercise, obesity and pregnancy all tend to promote the formation of varicose veins. Sometimes varicose veins are painful, but elevating the affected leg usually brings significant relief. Symptoms of varicose veins may include a dull pain, itch or heavy sensation in the legs. The sensation is worse after prolonged standing and better when the legs are elevated. Varicose veins typically appear on the legs as dilated, tortuous veins close to the surface of the skin, and may look blue. Advanced varicose veins may cause ankle and leg swelling or skin ulcers.

Fortunately there are herbs and nutrients that can help to support healthy vein function and blood circulation. These include horse chestnut, grape seed, ginkgo biloba and gotu kola, as well as rutin. Prolife Vein-care has included these ingredients in the formulation for individuals that are prone to suffer from CVI and varicose veins.

Grape seed contains a high level of proanthocyanidins, also known as OPCs, which belong to the flavonoid family, a class of water-soluble plant pigments. OPCs have antioxidant activity and they play a role in the stabilization of collagen and maintenance of elastin. These two proteins are found in connective tissues that support organs, joints, blood vessels and muscle. OPCs have been shown to strengthen capillaries, improve aspects of vision, and prevent abnormal blood clotting in smokers.

 Italian researchers underwent a clinical and capillaroscopic evaluation of the use of OPCs in patients with non-complicated CVI. 24 patients completed the study and they were given OPCs daily. The patients were examined to evaluate the efficacy of the OPCs using an instrumental evaluation by optical probe capillaroscope, as well as the traditional subjective clinical parameters, which included swelling, itching, heaviness and pain.  

 The results show a positive clinical response in over 80% of patients, with significant improvement of symptoms already evident after the first 10 days of treatment. The mechanism of action of the OPCs explains the rapid reduction of the swelling of the lower limbs. Itching and pain had completely disappeared in 80% and 53% of the patients respectively. A total of 70% of patients experienced improvement. There was no report of adverse events during the study. These findings justify the use of OPCs in the treatment of non-complicated CVI.  

Horse chestnut is native to Asia and northern Greece, but it is now cultivated in many areas of Europe and North America. This plant is a valuable herb used for strengthening veins. It is particularly useful for vein problems such as varicose veins and haemorrhoids.

In German, a meta-analysis of randomised controlled trials and large observational studies was conducted on the efficacy, routine effectiveness, and safety of horse chestnut in the treatment of CVI. Using a systematic literature search, 13 randomised controlled trials of CVI (1,051 patients) and 3 observational studies (10,725 patients) were identified. Examined outcomes were leg volume, ankle and calf circumference, edema, pain, sensation of tension, swelling, leg fatigue/heaviness, calf cramps and itching.  

The randomised controlled trials indicated that horse chestnut improved symptoms in patients with CVI. Compared to placebo, horse chestnut reduced leg volume and increased the likelihood of improvement in leg pain. Similarly, improvement probabilities were increased for edema and itching. Observational studies showed significant effectiveness regarding pain, edema and leg fatigue/heaviness. No severe adverse events were reported, and horse chestnut did not significantly increase mild adverse events. Based on meta-analyses of randomised controlled trials and observational studies, horse chestnut appears to be an effective and safe treatment for CVI.

Ginkgo biloba is the world’s oldest living tree species. Its leaves have been used in modern herbal medicine. Ginkgo has many valuable effects including stabilising cell membranes, reducing free radical damage, improving blood circulation and enhancing oxygen and glucose use. It is particularly beneficial for brain, nerves and blood vessels.  

The effect of ginkgo biloba on blood fluidity and cutaneous microcirculation was studied in a randomised, placebo controlled, single-blind cross-over study. A total of 10 apparently healthy subjects were given ginkgo biloba. Microcirculation was measured before and every 30 minutes for 4 hours after administration of ginkgo biloba, and fluidity of blood was determined before and after 1, 2 and 4 hours. There was a remarkable decrease on the erythrocyte aggregation observed 2 hours after administration of ginkgo biloba.  

The blood flow in the nail fold capillaries increased significantly 1 hour after administration. This study demonstrates that ginkgo biloba is useful for enhancing the fluidity and circulation of blood.
Mehlsen J. et al carried out a randomised, double-blinded cross-over study to validate possible vasodilating effects of a ginkgo biloba extract. The effect of ginkgo biloba extract was studied on forearm haemodynamics in 16 healthy subjects with a median age of 32 years using oral treatment with ginkgo biloba extract or placebo for 6 weeks. Forearm blood flow and venous capacity were measured by strain-gauge plethysmography. Measurements were made at baseline and after 3, 6, 9 and 12 weeks of treatment.

Forearm blood flow was significantly higher in the ginkgo group after 3 and 6 weeks as compared with placebo group for 3 and 6 weeks. It is concluded that oral treatment with a ginkgo biloba extract is able to dilate forearm blood vessels causing increments in regional blood flow without changing blood pressure levels in healthy subjects.

Rutin is a glycoside of the flavonol quercetin. It possesses many activities including antioxidant, anti-inflammatory and anti-platelet.

The inhibitory mechanisms of rutin in the platelet aggregation were studied in human platelets. The study indicates that the anti-platelet activity of rutin may involve several pathways. Rutin inhibits the activation of phospholipase C, and protein kinase C activity and thromboxane A(2) formation. Thereby this leads to inhibition of the phosphorylation of P47 and intracellular calcium mobilization. And finally it results in inhibition of platelet aggregation.  

Gotu kola has been an important herb in the medicinal systems of central Asia. In Sri Lanka, it was purported to prolong life. This herb has wound-healing and sedative properties. Gotu kola also has a historical reputation for boosting mental activity and for helping a variety of illnesses, such as high blood pressure, rheumatism, fever, insomnia and nervous disorders.

Pointel J.P. et al investigated the use of gotu kola in the treatment of venous insufficiency of the lower limbs in a multi-centre, double-blind, placebo-controlled study. Ninety-four patients suffering from CVI of the lower limbs participated in the study. After randomisation, they were allotted for a daily treatment period of two months to one of three groups, high dose of gotu kola, low dose of gotu kola or placebo.  

There was a significant difference in favour of gotu kola groups. It was shown in the symptoms of heaviness in the lower limbs and edema, as well as for the overall evaluation by the patient. The venous distensibility measured by a mercury strain gauge plethysmograph at three occlusion pressures was improved in the gotu kola groups but aggravated for the placebo group. This study showed that gotu kola might be useful for CVI as it helped to improve the symptoms of heaviness in the lower limbs and oedema, as well as enhancing the venous distensibility.

In summary, Vein-care contains potent herbs including horse chestnut, grape seed, ginkgo biloba and gotu kola, as well as rutin, which help to protect the integrity of veins and capillaries, as well as tone and strengthen vein walls. The ingredients in Vein-care support healthy vein and capillary function, and aid the blood circulation in the lower extremities. Vein-care is a useful supplement for those suffering from CVI and varicose veins.  

Costantini A., De Bernardi T., Gotti A., Clinical and capillaroscopic evaluation ofchronic uncomplicated venous insufficiency with procyanidins extracted from vitisvinifera, Minerva Cardioangiol. 1999 Jan-Feb; 47 (1-2): 39-46.GNC Healthnotes: www.gnc.comJung F., Mrowietz C., Kiesewetter H., Wenzel E., Effect of Ginkgo biloba on fluidity ofblood and peripheral microcirculation in volunteers. Arzneimittelforschung. 1990 May;40 (5): 589-93.Mehlsen J., Drabaek H., Wiinberg N., Winther K., Effects of a Ginkgo biloba extracton forearm haemodynamics in healthy volunteers. Clin Physiol Funct Imaging. 2002Nov; 22 (6): 375-8.Pointel J.P., Boccalon H., Cloarec M., Ledevehat C., Joubert M., Titrated extract ofCentella asiatica (TECA) in the treatment of venous insufficiency of the lower limbs.Angiology. 1987 Jan; 38 (1 Pt 1): 46-50.Reavley N., The New Encyclopedia of Vitamins, Minerals, Supplements and Herbs,Bookman Press, Melbourne, 1998.Sheu J.R., Hsiao G., Chou P.H., Shen M.Y., Chou D.S., Mechanisms involved in theantiplatelet activity of rutin, a glycoside of the flavonol quercetin, in human platelets, JAgric Food Chem. 2004 Jul 14; 52 (14): 4414-8.Siebert U., Brach M., Sroczynski G., Berla K., Efficacy, routine effectiveness, andsafety of horsechestnut seed extract in the treatment of chronic venous insufficiency.A meta-analysis of randomized controlled trials and large observational studies. IntAngiol. 2002 Dec; 21 (4): 305-15.


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